ABSTRACT
PURPOSE: As the incidence of non-typhoidal salmonella strains resistant to antibiotics has been increased, we attempted to investigate clinical aspects of non-typhoidal salmonella gastroenteritis and antibiotics resistance. METHODS: From January 2000 to June 2002, 99 children with positive stool culture of non-typhoidal salmonella were studied about clinical features, the incidence of antibiotics and multi-drug resistance and the difference of incidence of antibiotics resistance according to immune status. RESULTS: There were 66 males and 33 females. The majority of them were under 5 years of age (71%). 25 children were immunocompromised due to chemotherapy, steroid or immunosuppressive treatment. Serogroup D was the most common isolates (65%) followed by B (16%), C (8%) and E (8%). Resistance rate of 30% to ampicillin, 12% to chloramphenicol, 20% to trimethoprim- sulfamethoxazole (TMP-SMX), 11% to cefotaxime and 8% to cefixime were obtained. All isolates were susceptible to ciprofloxacine. Resistance rate to cefotaxime and cefixime in immunocompromised patients was 24% and 14.3% respectively, which were significantly higher compared to that in immunocompetent patients (6.8%, 5.6%, p<0.05). 11 isolates were resistant to three or more antibiotics. The incidence of multi-drug resistant isolates was significantly higher in immunocompromised patients (24%) than that of immunocompetent patients (6.8%). CONCLUSION: Because of the high prevalence of non-typhoidal salmonella strains resistant to ampicillin, chloramphenicol and TMP-SMX, third-generation cephalosporin might be the treatment of choice in non-typhoidal salmonella gastroenteritis. In particular, antibiotics should be carefully selected in immunocompromised patients because non-typhoidal salmonellas from them showed the higher incidence of antibiotic resistance and multi-drug resistance.
Subject(s)
Child , Female , Humans , Male , Ampicillin , Anti-Bacterial Agents , Cefixime , Cefotaxime , Chloramphenicol , Ciprofloxacin , Drug Resistance, Microbial , Drug Resistance, Multiple , Drug Therapy , Gastroenteritis , Immunocompromised Host , Incidence , Prevalence , Salmonella , Sulfamethoxazole , Trimethoprim, Sulfamethoxazole Drug CombinationABSTRACT
PURPOSE: We reviewed the functional and radiological results of unstable intraarticular fractures of the distal radius treated by percutaneous pinning with an external fixator. MATERIALS AND METHODS: Twenty-seven cases of unstable intraarticular fractures of the distal radius were treated by percutaneous pinning and external fixation between October 1996 and September 1999, and followed up for more than 1 year. We classified them using the Frykman classification and evaluated functional and radiological results according to the subjective point system of Cole & Obletz and the objective evaluation by Scheck. RESULTS: Subjectively, we obtained the following results: excellent in 7 cases, good in 13 cases, fair in 6 cases and poor in 1 case, and objectively, 8 cases were excellent, 14 cases were good, 4 cases were fair and 1 case was poor. Radiographically, mean volar tilt, radial inclination and radial length were 9.5degrees, 22.1degrees and 10.3 mm respectively on the last follow-up. Two cases of reflex sympathetic dystrophy and one of each of skin necrosis, pin tract infection, joint stiffness and metacarpal bone fracture occurred during the follow-up period. CONCLUSION: Percutaneous pinning and external fixation is a useful method for reducing mal-alignment and radial length maintenance, preventing reduction loss and restoring the articular surface and function of the distal radius in cases of intraarticular comminution, open fracture with soft tissue injury and multiple injury.
Subject(s)
Classification , External Fixators , Follow-Up Studies , Fractures, Bone , Fractures, Open , Intra-Articular Fractures , Joints , Multiple Trauma , Necrosis , Radius , Reflex Sympathetic Dystrophy , Skin , Soft Tissue InjuriesABSTRACT
It has been suggested that arginine vasopressin is involved in the acute, but not chronic, regulation of blood pressure. It is still debatable on the role of arginine vasopressin in the development and maintenance of high blood pressure, especially in renal hypertension. This study was performed to examine antidiuretic and renal hemodynamic effects of extremely low doses of arginine vasopressin and the modification of the effects in the early phase of two-kidney one clip Goldblatt hypertensive rabbits. Very low doses(up to 10-20mole/kg/min) of intrarenal arginine vasopressin induced decreases in urine volume, free water clearance, glomerular filteration rate and renal plasma flow(CPAH). The renal effects of arginine vasopressin were dose-dependent. These data indicate that the sensitivity of the kidney to decrease urine volume in response to arginine vasopressin is at least three orders of magnitude higher than previously reported. The renal effects of arginine vasopressin was significantly attenuated by the pretreatment of V2-receptor antagonist. The antidiuretic and renal hemodynamic effects elicited by very low doses of intrarenal arginine vasopressin were suppressed in the contralateral unclipped kidney of two-kidney, one clip Goldblatt hypertensive rabbits. These data suggest that the renal functions can be regulated normally by an extremely low concentration of plasma arginine vasopressin and the regulatory mechanism controlled by the ultralow plasma levels of arginine vasopressin is suppressed in the early phase of two-kidney, one clip Goldblatt hypertension.
Subject(s)
Rabbits , Arginine Vasopressin , Arginine , Blood Pressure , Hemodynamics , Hypertension , Hypertension, Renal , Hypertension, Renovascular , Kidney , Plasma , WaterABSTRACT
The size of spinal canal is mesured to detect the lumbar spinal stenosis syndrome and expanding intraspinaltumors by CT. This study was desinged for taking accurate measurement of the normal lumbar spinal canal in Koreanadults. The anteroposterior diameter, interpediculate distance and cross-sectional area of lumbar spinal canalwere measured in 110 normal adults. The results were as follows; 1. The window center that showed identical valueconsistent with actual measurement of phantom was between + 160HU and + 240HU and the window width was below +300HU. 2. In anteroposterio diameter, upper part of the canal was larger value than that of middle and lowerparts, but in interpediculate distance, lower part of the canal revealed larger value than that of upper andmiddle parts. There was no significant difference in cross-sectional area. 3. All measurements male were largerthan those of female at all levels of the spinal canal and 42 measurements(58%) were significant statisstically.4. Compared with Americans, Korean showed lower value in anteriopsterior diameter and cross-sectional area buthigher value in interpediculate distance. 5. Above results should contribute to making an another criteria fordiagnosing the lumbar spinal stenosis in Koreans.
Subject(s)
Adult , Female , Humans , Male , Asian , Spinal Canal , Spinal StenosisABSTRACT
Physiotherapy, psychotherapy, hormone therapy, chemical therapy, traditional surgical methods; amputation of painful extremities, cordotomy, leucotomy, rhizotomy, electrode insertion into the dorsal column of cord and acupuncture have been performed for therapeutic approaches to pain relief, but still there are problems in management of complete relief for the chronic pain today. At present, another new method of eliminating chronic pain is based on expanding the neurophysiologic aspect. Among the above mentioned therapeutic approaches to chronic pain relief, spinal barbotage seems to be least stressful to the patient and very effective in some cases. We have experienced a case of successful control of chronic pain by spinal barbotage for a 62 year old woman with metastatic colon carcinoma. The patient was well controlled chronic pain for 28 hours after the first spinal barbotage and for 3 weeks after the second spinal barbotage. It is considered that spinal barbotage is more simple, convenient and effective than other methods for intractable pain relief.
Subject(s)
Female , Humans , Middle Aged , Acupuncture , Amputation, Surgical , Chronic Pain , Colon , Cordotomy , Electrodes , Extremities , Pain, Intractable , Psychosurgery , Psychotherapy , RhizotomyABSTRACT
The question of infectivity and prevalence of Clonorchis sinensis in Cheju province (Quelpart Island) was arisen to authors since the several surveys on the endemic diseases were performed in this island. Therefore, authors decided to solute this question. Then the survey on the possible second intermediate host of Clonorchis sinensis was performed and reported already with negative finding. At present time, authors carried out the collection of all kinds of fresh-water snails through all areas of this island, to confirm the presence or not of Parafossarulus manchouricus, the only first intermediate host of Clonorchis sinensis in Korea . And the following results were obtained. The fresh-water snails collected in the survey were Semisulcospira libertina Gould and Lymnaea ollula Gould. Parafossarulus manchouricus Bourguigant was not collected in this island. It is confirmed that the Clonorchis sinensis can not be prevalent in this island.